C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 493/04 (2006.01) C12P 17/08 (2006.01)
Patent
CA 2695671
The present invention relates to improved methods for the production, isolation and purification of epothilone B. These methods include, for example, a fermentation process for the production of epothilone B, isolation via adsorption onto a resin, and subsequent purification.
Benigni Daniel
Chiang Shu-Jen
Comezoglu Fahri T.
Davis Brian L.
Eagan Bruce
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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