Microfabricated structures for facilitating fluid...

B - Operations – Transporting – 81 – B

Patent

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B81B 1/00 (2006.01) B01J 19/00 (2006.01) B01L 3/00 (2006.01) B01L 3/02 (2006.01) G01N 27/447 (2006.01) G01N 35/00 (2006.01) G01N 35/10 (2006.01)

Patent

CA 2290633

The microfluidic flow introduction system (30) includes a microfluidic substrate (32) having an array of through-hole ports (34). Samples and other fluids are transferred into through-hole ports (34) as drops on the outer surfaces of a corresponding array of pins (38). Through-holes (34) extend entirely through substrate (32) from an upper surface (40) to a lower surface (42). Drops will wick into through-hole ports (34) and will be restrained within the through-hole ports by capillary forces between the fluid and the surrounding ports. A fluid removal system (44) includes rods (46) which facilitate decanting the fluid from the through-hole ports (34).

L'invention concerne un système d'introduction (30) pour flux microfluidiques comprenant un substrat microfluidique (32) pourvu d'un ensemble d'orifices (34) traversants. Les échantillons et autres fluides sont transférés dans les orifices traversants (34) sous forme de gouttes situées sur la surface extérieure d'un ensemble d'aiguilles (38) correspondant. Les trous traversants (34) traversent entièrement le substrat (32) d'une surface supérieure (40) à une surface inférieure (42). Les gouttes tombent par effet de mèche dans les orifices traversants (34) et sont retenues à l'intérieur des orifices traversants par des forces capillaires qui s'exercent entre le fluide et l'orifice environnant. Un système (44) d'extraction de fluide comporte des tiges (46) qui facilitent la décantation du fluide dans les orifices traversants (34).

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