Novel peptides as ns3-serine protease inhibitors of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 5/08 (2006.01) A61K 31/16 (2006.01) A61K 31/195 (2006.01) A61K 31/27 (2006.01) A61K 31/357 (2006.01) A61K 31/385 (2006.01) A61K 31/403 (2006.01) A61K 31/4164 (2006.01) A61K 31/445 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07C 229/00 (2006.01) C07C 233/05 (2006.01) C07C 271/08 (2006.01) C07C 271/32 (2006.01) C07D 209/02 (2006.01) C07D 211/04 (2006.01) C07D 233/56 (2006.01) C07D 317/10 (2006.01) C07D 319/04 (2006.01) C07D 339/02 (2006.01) C07D 339/08 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2

Patent

CA 2410682

The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.

La présente invention concerne de nouveaux composés peptidiques qui possèdent une activité inhibitrice de la protéase du virus de l'hépatite C, et des procédés de préparation de ces composés. Dans un autre mode de réalisation, l'invention concerne des compositions pharmaceutiques comprenant les composés précités et des procédés d'utilisation de ces dernières dans le traitement de troubles associés à la protéase du virus de l'hépatite C.

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