C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/04 (2006.01) A23C 9/20 (2006.01) A61K 39/02 (2006.01) A61K 39/08 (2006.01) A61K 39/395 (2006.01) A61K 39/40 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2389582
The present invention provides means and methods for obtaining an antibody in a mammary secretion product of a farm-animal comprising administering to said animal at least two compositions, which may be the same or different, comprising an antigen to which said antibody is to be raised, the method comprising administering at least a first of said compositions such that a high mucosal and/or systemic immune response is obtained and wherein at least a second of said compositions is administered to a mammary gland and/or a supramammary lymph node of said animal.
La présente invention concerne des procédés et des moyens visant à l'obtention d'un anticorps dans un produit de sécrétion mammaire d'un animal d'élevage. A cet effet, on administre à cet animal au moins deux compositions identiques ou différentes comprenant un antigène contre lequel doit être dirigé l'anticorps. Pour ce procédé, on prend, d'une part au moins une première de ces compositions destinées à conférer une réponse immunitaire muqueuse et/ou systémique élevée, et d'autre part au moins une seconde de ces compositions, et on les administre au niveau d'une grande mammaire et/ou d'un ganglion lymphatique supramammaire de l'animal considéré.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Muco Vax B.v.
W. Health L.p.
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