Triazolotriazines as kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 487/04 (2006.01) A61K 31/53 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2660836

The present invention is directed to [l,2,4]mazolo[4,3-b][l,2,4]triazines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. (I)

La présente invention concerne des [1,2,4]triazolo[4,3-b][1,2,4]triazines et des compositions pharmaceutiques les contenant qui sont des inhibiteurs des kinases telles que c-Met et qui sont utilisées pour le traitement du cancer et d'autres maladies liées aux perturbations des voies des kinases. formule (I)

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