Unsymmetrical cyclic diamine compound

Details Unsymmetrical cyclic diamine compound Unsymmetrical cyclic diamine compound

C - Chemistry, Metallurgy

07

D

C07D 213/72 (2006.01) A61K 31/496 (2006.01) A61K 31/506 (2006.01) A61K 31/551 (2006.01) A61P 9/10 (2006.01) A61P 11/06 (2006.01) A61P 29/00 (2006.01) A61P 37/08 (2006.01) A61P 43/00 (2006.01) C07D 213/36 (2006.01) C07D 213/81 (2006.01) C07D 213/82 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2451241

A cyclic diamine compound of formula (1): (see formula 1) wherein A is (CH2)n, (CH2)n-CH=CH, CO- (CH2)n or CO-(CH2)n- CH=CH, in which n is a number of 0 to 3; Z represents a formula (2) or (3): (see formula 2) (see formula 3) in which R1, R2, R4, R5 and R6 are individually a hydrogen atom, alkyl group, and X and Y are individually CH or a nitrogen atom; and m is 1 or 2; an acid-addition salt thereof, or a hydrate thereof, and a medicine containing such a compound, having excellent effects on both adhesion and cell infiltration, as well as being useful for the prevention and treatment of allergy, asthma, inflammation, rhumatism, and orteriosclerosis. 120

L'invention concerne un composé diamine représenté par la formule générale (I), dans laquelle A représente (CH¿2?)¿n?, (CH¿2?)¿n?-CH=CH, CO-(CH¿2?)¿n?, ou CO-(CH¿2?)¿n?-CH=CH, n valant un entier de 0 à 3 ; Z représente la formule (2) ou (3), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿ et R?6¿ sont identiques ou différents et représentent chacun hydrogène, alkyle, etc., X et Y sont identiques ou différents et représentent chacun CH ou azote) ; et m vaut 1 ou 2. L'invention porte sur un sel d'addition d'acide du composé, sur un hydrate du sel ou du composé, et sur un médicament contenant l'un d'eux. Ledit composé (1) possède une activité inhibitrice excellente contre l'infiltration cellulaire et l'adhésion cellulaire. Il (1) est utile dans la prévention et le traitement, entre autres, de l'allergie, de l'asthme, des rhumatismes, de l'artériosclérose, de l'inflammation.

Affiliated with

Also associated with

Rating

Unsymmetrical cyclic diamine compound does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Unsymmetrical cyclic diamine compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Unsymmetrical cyclic diamine compound will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1512621